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Mitochondrial fission and fusion

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Mitochondrial fission and fusion protects against cardiac complications.
“modulating mitochondrial dynamics with either fission inhibitors or fusion promoters has offered cardioprotection against these pathological conditions in preclinical models.”
Reviewin preclinical models of aging and obesity
Future perspectives on the roles of mitochondrial dynamics in the heart in obesity and aging
Life sciencesMar 14, 2024

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Mice lacking the receptor also showed higher inflammation, elevated DNA damage, and a five-month reduction in median lifespan.Mice lacking the receptor also showed higher inflammation, elevated DNA damage, and a five-month reduction in median lifespan.

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bioRxivJul 16

Heme drives cardiac endothelial senescence in sepsis via STING activation

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Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes

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Archives of Gerontology and GeriatricsApr 27

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Radiation ResearchMar 10

Widespread Multimorbidity in a Cohort of Aging, Radiation-exposed Rhesus Macaques

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Future perspectives on the roles of mitochondrial dynamics in the heart in obesity and aging

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Frontiers in PhysiologyDec 13

Modelling premature cardiac aging with induced pluripotent stem cells from a hutchinson-gilford Progeria Syndrome patient

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