Apparent treatment-resistant hypertension

1. Clonal hematopoiesis of indeterminate potential is associated with apparent treatment-resistant hypertension in humans (~23% vs ~7%).

   “CHIP was detected in ~23% of patients with aTRH versus ~7% of matched controlled-hypertension controls.”

   Humansversus ~7% of matched controlled-hypertension controls

   Clonal hematopoiesis in apparent treatment-resistant hypertension, insights from multiple medical centers and community-based cohorts

   Nature aging·24 Nov 2025

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