Zonation marker expression

Biomarker

1 paper1 finding

Animals1

Associations

Senescence signatures

mixedin mice1

1 study

Senescence signatures are associated with zonation marker expression in mice.
“Multiple analytic approaches identified distinct age-, zone- and sex-specific senescence signatures, which were significantly associated with zonation markers changes.”
Animalswild-type miceliver
Senescence linked to loss of liver zone identity in mice
bioRxiv : the preprint server for biology10 Aug 2026Preprint

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bioRxiv8 Oct

Senescence linked to loss of liver zone identity in mice

An animal study mapped gene activity in mouse livers of multiple ages, linking senescence patterns to changes in gene patterns defining specialised liver zones.An animal study mapped gene activity in mouse livers of multiple ages, linking senescence patterns to changes in gene patterns defining specialised liver zones.

Preprint: experiments in miceCellular senescence

Paper

Zonation marker expression

Associations

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Senescence linked to loss of liver zone identity in mice

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