1 paper3 findings
Blood pressure
upin silico1
Blood pressure increases WMH volume in silico.
“increasing blood pressure (BP) with larger WMH-volume, notably also in persons without clinical hypertension”
In silicoin persons without clinical hypertension
Cerebral small vessel disease genomics and its implications across the lifespan
Nature communications8 Dec 2020
Alzheimer-type dementia
upin silico1
WMH volume raises the risk of Alzheimer-type dementia in silico.
“increasing WMH-volume with stroke, Alzheimer-type dementia”
In silico
Cerebral small vessel disease genomics and its implications across the lifespan
Nature communications8 Dec 2020
Stroke
upin silico1
WMH volume raises the risk of stroke in silico.
“Mendelian randomization suggested causal association of increasing WMH-volume with stroke”
In silico
Cerebral small vessel disease genomics and its implications across the lifespan
Nature communications8 Dec 2020
In a six-month trial of 51 people with vascular mild cognitive impairment, lower volumes of bright brain areas were linked to greater symptom reductions.In a six-month trial of 51 people with vascular mild cognitive impairment, lower volumes of bright brain areas were linked to greater symptom reductions.