Vitality Score

Biomarker

4 papers study it3 more mention it4 findings

  • Human trial1
  • Animals3

Interventions

1

LAV-BPIFB4 gene therapy

upin mice1

1 study
  1. LAV-BPIFB4 gene therapy improves Vitality Score in mice.

    “LAV-BPIFB4 gene transfer resulted in an improvement of the Vitality Score”

    Animalsaged

    Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice

    International journal of molecular sciences

More on LAV-BPIFB4 gene therapy

Associations

3

Epigenetic clock

upin mice1

1 study
  1. Vitality Score is associated with epigenetic clock in mice.

    “correlates with biomarkers related to the accumulation of senescent cells and the epigenetic clock.”

    Animals

    Comprehensive longitudinal non-invasive quantification of healthspan and frailty in a large cohort (n = 546) of geriatric C57BL/6 J mice

    GeroScience

More on Epigenetic clock

Cellular senescence

upin mice1

1 study
  1. Vitality Score is associated with cellular senescence in mice.

    “correlates with biomarkers related to the accumulation of senescent cells and the epigenetic clock.”

    Animals

    Comprehensive longitudinal non-invasive quantification of healthspan and frailty in a large cohort (n = 546) of geriatric C57BL/6 J mice

    GeroScience

More on Cellular senescence

Mortality

upin mice1

1 study
  1. Vitality Score predicts mortality in mice.

    “VS displays a higher association with mortality than PFS or CFI”

    Animals

    Comprehensive longitudinal non-invasive quantification of healthspan and frailty in a large cohort (n = 546) of geriatric C57BL/6 J mice

    GeroScience

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