Visual Short-Term Memory Binding Test

1. Visual Short-Term Memory Binding Test predicts Alzheimer's disease in humans (AUC = .722 (Aβ), AUC = 0.743 (tau)).

   “Among cognitive measures, VSTMBT was the most sensitive and accurate measure for detecting Aβ (AUC = .722) and tau-PET positivity (AUC=0.743)”

   Humansclinically unimpairedn = 80

   Discrimination tasks increase the value of plasma p ‐tau217 to predict presymptomatic Alzheimer's disease

   AAIC 2025 abstract·25 Dec 2025

More on Alzheimer's disease

1. Visual Short-Term Memory Binding Test predicts medial temporal tau burden in humans (b = -0.01, SE = 0.004, p = .004).

   “optimal model fit (initial AIC=4.88, final AIC=3.55) was found with the VSTMBT ( b = ‐0.01, SE=0.004, p = .004)”

   Humanscognitively unimpairedmedial temporal loben = 77

   Targeting pre‐symptomatic AD individuals: Deep cognitive assessment and plasma biomarkers to predict tau aggregation

   AAIC 2025 abstract·24 Dec 2025

1. Visual Short-Term Memory Binding Test predicts tau PET in humans (AUC=0.743).

   “detecting Aβ (AUC=.722) and tau‐PET positivity (AUC=0.743)”

   Humansclinically unimpaired older adults

   Discrimination tasks increase the value of plasma p ‐tau217 to predict presymptomatic Alzheimer's disease

   AAIC 2025 abstract·23 Dec 2025

More on Tau PET

1. Visual Short-Term Memory Binding Test predicts amyloid PET in humans.

   “Among cognitive measures, VSTMBT was the most sensitive and accurate measure for detecting Aβ (AUC=.722) and tau‐PET positivity (AUC=0.743)”

   Humansclinically unimpaired older adults

   Discrimination tasks increase the value of plasma p ‐tau217 to predict presymptomatic Alzheimer's disease

   AAIC 2025 abstract·23 Dec 2025

More on Amyloid PET