What does the research say about VDR protein expression?

VDR protein expression

There are 2 papers on VDR protein expression in aging research: 1 observational study in people, 1 in animals.

2 papers study it2 findings

See all 2 papers on VDR protein expression

“The density of VDR protein expressions was 2.1 times greater, while that of myostatin was 2.6 times lower, in the control group than in the sarcopenic group”

Altered gene and protein expressions of vitamin D receptor in skeletal muscle in sarcopenic patients who sustained distal radius fracturesJournal of bone and mineral metabolism2019doi:10.1007/s00774-019-00995-0

Humans1
Animals1

Upstream

Age

upin mice1

1 study

Age increases VDR protein expression in mice (mature and aged muscle compared with development).
“Compared with development, significant increases in vitamin D receptor (VDR) protein expression in mature and aged muscles”
Animalsmature and aged muscle compared with developmentskeletal musclemales
Regulation of vitamin D system in skeletal muscle and resident myogenic stem cell during development, maturation, and ageing
Scientific reportsMay 19, 2020

Associations

Sarcopenia

downin humans1

1 study

Sarcopenia is associated with VDR protein expression in forearm muscle of patients with distal radius fracture, Western blot (VDR protein density 2.1 times greater in controls than in sarcopenic group).
“The density of VDR protein expressions was 2.1 times greater, while that of myostatin was 2.6 times lower, in the control group than in the sarcopenic group”
Humansin forearm muscle of patients with distal radius fracture, Western blotskeletal musclen = 20
Altered gene and protein expressions of vitamin D receptor in skeletal muscle in sarcopenic patients who sustained distal radius fractures
Journal of bone and mineral metabolismFeb 21, 2019