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Tubular biomarkers

Biomarker

1 paper2 findings

  • Human trial1

Interventions

2

Caloric restriction

no changein humans1

1 study

  1. Caloric restriction has no effect on tubular biomarkers in humans.

    “Tubular biomarkers did not change with dietary-induced weight loss or metformin”

    Human trialpatients with ADPKD12 monthsn = 66

    Changes in tubular biomarkers with dietary intervention and metformin in patients with autosomal dominant polycystic kidney disease: a post-hoc analysis of two clinical trials

    BMC nephrologyJun 25, 2024

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Metformin

no changein humans1

1 study

  1. Metformin has no effect on tubular biomarkers in humans.

    “None of the tubular biomarkers changed with any intervention as compared to placebo.”

    Human trialpatients with ADPKD12 monthsn = 66

    Changes in tubular biomarkers with dietary intervention and metformin in patients with autosomal dominant polycystic kidney disease: a post-hoc analysis of two clinical trials

    BMC nephrologyJun 25, 2024

More on Metformin

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