TPOAb

1. TPOAb has no effect on stroke in humans (HR 0.98 (95% CI 0.87-1.11)).

   “HR 0.98 (95% CI 0.87-1.11) for stroke events”

   Humansn = 100,250

   SUN-256 Is Thyroid Antibody Testing Useful to Predict the Risk of Coronary Heart Disease and Stroke Independently of Thyroid Function? An Individual Participant Data Analysis.

   ENDO 2025 abstract·22 Oct 2025

More on Stroke

1. TPOAb has no effect on coronary heart disease in humans (HR 1.00 (95% CI 0.90-1.11)).

   “We found no evidence of a risk difference between participants with positive vs. negative TPOAb in the overall population: HR 1.00 (95% CI 0.90-1.11) for CHD events”

   Humansn = 100,250

   SUN-256 Is Thyroid Antibody Testing Useful to Predict the Risk of Coronary Heart Disease and Stroke Independently of Thyroid Function? An Individual Participant Data Analysis.

   ENDO 2025 abstract·22 Oct 2025

More on Coronary heart disease

1. TPOAb is associated with stroke in humans (HR 0.68 (95% CI 0.51 to 0.90)).

   “Among participants with subclinical hypothyroidism, positive vs. negative TPOAb HRs were 0.87 (95% CI 0.72 to 1.05) for CHD events, 0.88 (95% CI 0.64 to 1.21) for CHD mortality, 0.68 (95% CI 0.51 to 0.90) for stroke events”

   Humansin subclinical hypothyroidism

   SUN-256 Is Thyroid Antibody Testing Useful to Predict the Risk of Coronary Heart Disease and Stroke Independently of Thyroid Function? An Individual Participant Data Analysis.

   ENDO 2025 abstract·22 Oct 2025

More on Stroke