Total kidney volume
1 paper1 finding
- Human trial1
Interventions
1Rapamycin
no changein humans1
1 study
Rapamycin
no changein humans1
Rapamycin has no effect on total kidney volume in humans (102% of control (95% CI, 99 to 105; P=0.26)).
“At 18 months, the median total kidney volume in the sirolimus group was 102% of that in the control group (95% confidence interval, 99 to 105; P=0.26).”
Human trialautosomal dominant polycystic kidney diseasekidneytarget dose, 2 mg daily18 monthsn = 100
Sirolimus and kidney growth in autosomal dominant polycystic kidney disease
The New England journal of medicine26 Jun 2010
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Sirolimus and kidney growth in autosomal dominant polycystic kidney disease
Randomised trial in 100 peopleRapamycin