Total EEG approximate entropy

Cognitive impairment severity is associated with total EEG approximate entropy in humans.

“Significant group differences in total ApEn were found, particularly in central brain regions, with progressive decreases from HE to MCI and AD.”

Humanscomparison of healthy elderly, mild cognitive impairment, and Alzheimer's disease groupsbrain, particularly central regionsn = 269

Electroencephalographic complexity and cognitive decline: Insights from approximate entropy across aging and dementia

Alzheimer's & dementia (New York, N. Y.)·11 Oct 2026