Total DNA polymerase activity

1. Caloric restriction decreases total DNA polymerase activity in rats.

   “cerebellum registered a decrease during all periods of restriction”

   Animalscerebellummales

   Long-term effects of caloric restriction initiated at different ages on DNA polymerases in rat brain

   Mechanisms of ageing and development·Dec 20, 1996

2. Caloric restriction increases total DNA polymerase activity in rats.

   “CR had a greater stimulatory response on the activity of total DNA polymerases measured at 28 months of age in rats restricted from 6 to 28 months of age”

   Animalsinitiated at 6 months of agebrain6 to 28 months of agemales

   Long-term effects of caloric restriction initiated at different ages on DNA polymerases in rat brain

   Mechanisms of ageing and development·Dec 20, 1996

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