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TNF promoter DNA methylation

There is 1 paper on TNF promoter DNA methylation in aging research: none in people yet, 1 in animals.

Biomarker

1 paper studies it1 finding

See all 1 papers on TNF promoter DNA methylation

  • Animals1

Interventions

1

Caloric restriction

upin rats1

1 study

  1. Caloric restriction increases TNF promoter DNA methylation in rats.

    “Muscle qPCR analysis showed a marked decrease in inflammation and TNF (premRNA, mRNA, and protein) by CR, accompanied by Tnf promoter DNA hypermethylation.”

    AnimalsAIN93M with 75% of energy requirementskeletal muscle75% of energy requirementsix monthsmales

    Caloric restriction following early-life high fat-diet feeding represses skeletal muscle TNF in male rats

    The Journal of nutritional biochemistry

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