TNF-α, IL-6, IL-23, and IL-33 secretion

1. Diesel exhaust particles increase TNF-α, IL-6, IL-23, and IL-33 secretion in human cells.

   “DEP induced a rapid response, increasing TNF-α, IL-6, IL-23, and IL-33 within 2 hr in young MDMi and 24 hr in aged MDMi.”

   CellsCells derived from healthy individualsmonocyte-derived microglia-like cellsWithin 2 hours in young MDMi and 24 hours in aged MDMi

   Impact of wildfire smoke and diesel exhaust on inflammatory response in aging human microglia

   bioRxiv (Cold Spring Harbor Laboratory)·20 Dec 2024Preprint

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