Thalamocortical neuron loss

1 paper1 finding

Animals1

Interventions

1

AAV9

downin mice1

1 study

AAV9 prevents thalamocortical neuron loss in mice.
“as well as thalamic reactive gliosis and thalamocortical neuron loss in treated Hexb-/- mice.”
Animalsin Hexb-/- Sandhoff disease micethalamus
Intravenous administration of scAAV9-Hexb normalizes lifespan and prevents pathology in Sandhoff disease mice
Human molecular genetics15 Mar 2018

Latest

Human Molecular Genetics15 Mar

Intravenous administration of scAAV9-Hexb normalizes lifespan and prevents pathology in Sandhoff disease mice

Experiments in miceInterventions