Tenocyte cellularity

1 paper1 finding

Animals1

Upstream

1

SCX

downin mice1

1 study

SCX decreases tenocyte cellularity in mice.
“depletion of Scleraxis-lineage cells in young mice (Scx-DTR). Scx-DTR recapitulates many aspects of tendon aging including comparable declines in cellularity”
Animalsvia depletion of Scleraxis-lineage cellstendon
Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype
eLife19 Jan 2023

Latest

eLife19 Jan

Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype

Experiments in miceProteostasis