Temporal muscle thickness

There are 27 papers on temporal muscle thickness in aging research: 26 observational studies in people, 1 review.

Biomarker

27 papers study it8 more mention it46 findings

See all 35 papers on temporal muscle thickness

“Lower average TMT was significantly associated with a higher likelihood of poor functional outcomes (OR = 0.560, 95% CI: 0.391-0.804, p = 0.002).”
Predictive value of temporal muscle thickness in patients with chronic subdural hematomaFrontiers in neurology2026doi:10.3389/fneur.2025.1704557
  • Humans26

Effects

4

Physical function

upin humans1no changein humans1OR 0.791

2 studies
  1. Temporal muscle thickness is linked with better physical function in humans (multivariable logistic regression) (OR: 0.791, 95% CI: 0.670-0.935, p < 0.01).

    “reduced likelihood of functional dependence (OR: 0.791, 95% CI: 0.670-0.935, p < 0.01)”

    Humansmultivariable logistic regressionn = 801

    Temporal Muscle Thickness as a New Biomarker: Its Association With Alzheimer Pathology and Cognitive Impairment in Chinese Adults

    Journal of cachexia, sarcopenia and muscle

  2. Temporal muscle thickness was not clearly linked with physical function in humans (r = -0.000, p = 0.998).

    “However, no significant correlation was observed between TMT and physical performance (r = -0.000, p = 0.998).”

    Humansn = 28

    Temporal Muscle Thickness and Sarcopenia Components in Healthy Adults, Validated through Allgeun Diagnostic Tool

    Healthcare (Basel, Switzerland)

Lifespan

downin humans2HR 1.86

2 studies
  1. Temporal muscle thickness is linked with shorter lifespan in humans (undergoing surgical CSDH drainage) (HR 1.86, 95% CI 1.02-3.36).

    “TMT below these cut-offs was associated with shorter survival in both univariate (HR 3.24, 95% CI 1.85-5.67) and multivariate (HR 1.86, 95% CI 1.02-3.36) analyses”

    Humansundergoing surgical CSDH drainagen = 188

    Reduced temporal muscle thickness predicts shorter survival in patients undergoing chronic subdural haematoma drainage

    Journal of cachexia, sarcopenia and muscle

  2. Temporal muscle thickness is linked with lower lifespan in humans (acute ischemic stroke) (36 vs 49 months).

    “Kaplan-Meier analysis showed that the survival time of low TMT group was significantly lower than that of high TMT group (36 vs 49 months; P < .001).”

    Humansacute ischemic stroken = 265

    Long-term prognostic significance of sarcopenia in acute ischemic stroke

    Medicine

Cognitive function

upin humans1

1 study
  1. Temporal muscle thickness is linked with better cognitive function in humans (adjusted for confounders) (r = 0.124, p = 0.001).

    “TMT was positively correlated with Montreal Cognitive Assessment-Basic (MoCA-B) scores (r = 0.124, p = 0.001)”

    Humansadjusted for confoundersn = 801

    Temporal Muscle Thickness as a New Biomarker: Its Association With Alzheimer Pathology and Cognitive Impairment in Chinese Adults

    Journal of cachexia, sarcopenia and muscle

Grip strength

no changein humans1

1 study
  1. Temporal muscle thickness was not clearly linked with grip strength in humans (post-stroke hemiparesis).

    “No significant correlations were identified with age, BMI or handgrip strength.”

    Humanspost-stroke hemiparesisn = 45

    Association Between Temporal Muscle Thickness and Skeletal Muscle Mass, Nutritional Status, and Physical Function in Patients With Post-stroke Hemiparesis: A Cross-Sectional Study

    Cureus

Upstream

3

Chronological age

downin humans1

1 study
  1. Chronological age is linked with lower temporal muscle thickness in humans (r = -0.213, p < 0.001).

    “TMT showed a significant but low-level decrease with aging (r = -0.213, p < 0.001).”

    Humansn = 648

    Temporalis muscle thickness: Ultrasound measurement, clinical significance and correlation with sarcopenic indices

    Clinical nutrition (Edinburgh, Scotland)

Stroke

downin humans1

1 study
  1. Stroke is linked with lower temporal muscle thickness in humans (acute stroke) (5.85±0.96 on admission and 5.67±0.97 on third month (p=0.004)).

    “The mean temporal muscle thickness was 5.85±0.96 on admission and 5.67±0.97 on third month in the entire group (p=0.004).”

    Humansacute stroken = 114

    Does the thickness of temporal muscle indicate sarcopenia and functional outcome in older patients with acute stroke?

    Ideggyogyaszati szemle

More on Stroke

Isolated rapid eye movement sleep behavior disorder

downin humans1

1 study
  1. Isolated rapid eye movement sleep behavior disorder is linked with lower temporal muscle thickness in humans (isolated rapid eye movement sleep behavior disorder) (11.843 vs. 10.420 mm, p = 0.002).

    “The TMT was reduced in patients with isolated RBD than in healthy controls (11.843 vs. 10.420 mm, p = 0.002).”

    Humansisolated rapid eye movement sleep behavior disorder

    Sarcopenia in patients with isolated rapid eye movement sleep behavior disorder

    Sleep medicine

More on Isolated rapid eye movement sleep behavior disorder

Associations

26

Mortality

downin humans4upin humans2OR 0.708–1.42

6 studies
  1. Temporal muscle thickness is linked with a lower risk of mortality in humans (non-cancer palliative care patients).

    “In multivariable analysis, TMT remained independently associated with mortality, whereas CAR and NLR were not.”

    Humansnon-cancer palliative care patients3 monthsn = 134

    Temporal muscle thickness is superior to inflammatory markers in predicting 3-month mortality in older non-cancer palliative care patients

    BMJ supportive & palliative care

  2. Temporal muscle thickness predicts mortality in humans (non-cancer palliative care patients) (AUC=0.759).

    “TMT showed the most remarkable ability to predict mortality (area under the curve (AUC)=0.759), surpassing CAR (AUC=0.622) and NLR (AUC=0.610).”

    Humansnon-cancer palliative care patients3 monthsn = 134

    Temporal muscle thickness is superior to inflammatory markers in predicting 3-month mortality in older non-cancer palliative care patients

    BMJ supportive & palliative care

  3. Temporal muscle thickness predicts mortality in humans (surgically evacuated spontaneous intracerebral hemorrhage) (67% vs. 30%, HR 2.65, 95% CI 1.23-5.65).

    “overall mortality during the median follow-up period of 36 months (IQR 1-79) was significantly higher in the low muscle status group, as assessed using TMT and TMI cut-offs (67 % vs. 30 %, HR 2.65”

    Humanssurgically evacuated spontaneous intracerebral hemorrhagemedian 36 monthsn = 63

    Temporal muscle thickness and index predict overall survival after surgical evacuation of spontaneous intracerebral hemorrhage

    Clinical neurology and neurosurgery

  4. Temporal muscle thickness is linked with a lower risk of mortality in humans (acute ischemic stroke treated with revascularization procedures) (OR 0.708, 95% CI 0.538-0.930, p = 0.013).

    “higher TMT values resulted independently associated with reduced mortality (Odds Ratio 0.708, 95% Confidence Interval 0.538-0.930, p = 0.013)”

    Humansacute ischemic stroke treated with revascularization procedures3 monthsn = 261

    Temporalis muscle thickness as a predictor of functional outcome after reperfusion therapies for acute ischemic stroke: a retrospective, cohort study

    Journal of neurology

  5. Temporal muscle thickness predicts mortality in older adults with mild dementia (HR=0.815, p-value 0.002).

    “TMT and functional decline in DLB (Est.=-0.123, p-value 0.007) and increased mortality in the whole sample(HR=0.815, p-value 0.002)”

    Humansin older adults with mild dementia

    Temporal Muscle Thickness Predicts Mortality and Disability in Older Adults Diagnosed with Mild Dementia

    The Journal of frailty & aging

  6. Temporal muscle thickness is linked with a lower risk of mortality in humans (prevalent hemodialysis patients) (hazard ratio=0.740, p=0.035).

    “temporal muscle thickness was a significant predictor of mortality (hazard ratio=0.740, p=0.035)”

    Humansprevalent hemodialysis patientsn = 60

    Temporal muscle thickness predicts mortality in prevalent hemodialysis patients

    Revista da Associacao Medica Brasileira (1992)

  7. Temporal muscle thickness is associated with mortality in humans (stroke) (OR 1.42, 95% CI 1.03–1.96).

    “low TMT was associated with a statistically significant increase in the risk of post-stroke mortality (OR: 1.42 95% CI: 1.03, 1.96 I 2 = 43%)”

    Reviewstroke

    Value of temporal muscle thickness in predicting outcomes of stroke: a systematic review and meta-analysis

    Frontiers in neurology

Handgrip strength

upin humans3

3 studies
  1. Temporal muscle thickness is associated with handgrip strength in humans (r = 0.338).

    “A moderate correlation was found between TMT and HGS (r = 0.334 for HGS-maximum and r = 0.338 HGS-mean)”

    Humansn = 648

    Temporalis muscle thickness: Ultrasound measurement, clinical significance and correlation with sarcopenic indices

    Clinical nutrition (Edinburgh, Scotland)

  2. Temporal muscle thickness is associated with handgrip strength in humans (r = 0.444, p = 0.018).

    “There were moderate positive correlations between TMT and calf circumference (r = 0.413, p = 0.029), thigh circumference (r = 0.486, p = 0.008), and handgrip strength (r = 0.444, p = 0.018).”

    Humansn = 28

    Temporal Muscle Thickness and Sarcopenia Components in Healthy Adults, Validated through Allgeun Diagnostic Tool

    Healthcare (Basel, Switzerland)

  3. Temporal muscle thickness is associated with handgrip strength in humans (Parkinson's disease) (r = 0.561, p < 0.001).

    “as well as handgrip strength (r: 0.561, p < 0.001).”

    HumansParkinson's diseasen = 32

    Temporal Muscle Thickness Correlates with Sarcopenia in Parkinson's Disease

    Journal of Parkinson's disease

Physical function

no changein humans1upin humans1OR 1.24

2 studies
  1. Temporal muscle thickness is associated with physical function in humans (acute ischemic stroke treated with revascularization procedures).

    “In univariate models, patients with excellent outcomes (mRS = 0-1) were younger, had higher TMT values”

    Humansacute ischemic stroke treated with revascularization procedures3 monthsn = 261

    Temporalis muscle thickness as a predictor of functional outcome after reperfusion therapies for acute ischemic stroke: a retrospective, cohort study

    Journal of neurology

  2. Temporal muscle thickness is associated with physical function in humans (stroke) (OR 1.24, 95% CI 1.00–1.54).

    “there was a tendency for good functional outcomes with high TMT (OR: 1.24 95% CI: 1.00, 1.54 I 2 = 75%). But the results were non-significant.”

    Reviewstroke

    Value of temporal muscle thickness in predicting outcomes of stroke: a systematic review and meta-analysis

    Frontiers in neurology

Cognitive function

upin humans2

2 studies
  1. Temporal muscle thickness is associated with cognitive function in humans (estimate = 0.168, P = .002).

    “TMT exhibited significant associations with MMSE (estimate = 0.168, P = .002)”

    Humansn = 657

    Temporal Muscle Thickness: A Practical Approximation for Assessing Muscle Mass in Older Adults

    Journal of the American Medical Directors Association

  2. Temporal muscle thickness is associated with cognitive function in Lewy body dementia at baseline (Est.=0.593, p-value=0.049).

    “At baseline TMT showed significant association with cognitive performance in the DLB group (Est.=0.593, p-value=0.049).”

    Humansin Lewy body dementia at baseline

    Temporal Muscle Thickness Predicts Mortality and Disability in Older Adults Diagnosed with Mild Dementia

    The Journal of frailty & aging

Chronic subdural hematoma

downin humans1OR 0.219

1 study
  1. Temporal muscle thickness is associated with chronic subdural hematoma in humans (OR = 0.219, 95% CI: 0.179-0.269).

    “CSDH more likely to develop on the side with lower TMT (OR = 0.219, 95% CI: 0.179-0.269).”

    Humans

    Predictive value of temporal muscle thickness in patients with chronic subdural hematoma

    Frontiers in neurology

  2. Chronic subdural hematoma is associated with temporal muscle thickness in humans (compared to control group) (p < 0.001).

    “TMT was significantly lower in patients with CSDH than in the control group (p < 0.001).”

    Humanscompared to control group

    Predictive value of temporal muscle thickness in patients with chronic subdural hematoma

    Frontiers in neurology

More on Chronic subdural hematoma

Chronological age

downin humans1

1 study
  1. Temporal muscle thickness is associated with chronological age in Parkinson's disease patients (r=-0.326, p=0.046).

    “There was a significant correlation between temporal muscle thickness and age (r=-0.326, p=0.046)”

    Humansin Parkinson's disease patientsn = 38

    Temporal muscle thickness: A new tool to assess sarcopenia in Parkinson's disease

    Ideggyogyaszati szemle

Sarcopenia risk

downin humans1

1 study
  1. Temporal muscle thickness is associated with sarcopenia risk in Parkinson's disease patients (r=-0.738).

    “There was a significant correlation between temporal muscle thickness and age (r=-0.326, p=0.046), SARC-F score (r=-0.738, p.”

    Humansin Parkinson's disease patientsn = 38

    Temporal muscle thickness: A new tool to assess sarcopenia in Parkinson's disease

    Ideggyogyaszati szemle

Functional outcome

downin humans1OR 0.56

1 study
  1. Temporal muscle thickness predicts functional outcome in patients with CSDH (OR = 0.560, 95% CI: 0.391-0.804, p = 0.002).

    “Lower average TMT was significantly associated with a higher likelihood of poor functional outcomes (OR = 0.560, 95% CI: 0.391-0.804, p = 0.002).”

    Humansin patients with CSDH

    Predictive value of temporal muscle thickness in patients with chronic subdural hematoma

    Frontiers in neurology

Dysphagia

upin humans1

1 study
  1. Temporal muscle thickness is associated with dysphagia in humans (stroke).

    “Two studies showed that baseline TMT was significantly associated with an increased risk of dysphagia.”

    Reviewstroke

    Value of temporal muscle thickness in predicting outcomes of stroke: a systematic review and meta-analysis

    Frontiers in neurology

More on Dysphagia

Mild cognitive impairment

downin humans1OR 0.494

1 study
  1. Temporal muscle thickness is linked with a lower risk of mild cognitive impairment in humans (multivariable logistic regression) (OR: 0.494, 95% CI: 0.287-0.849, p < 0.05).

    “higher TMT was significantly associated with a lower risk of MCI (OR: 0.494, 95% CI: 0.287-0.849, p < 0.05)”

    Humansmultivariable logistic regressionn = 801

    Temporal Muscle Thickness as a New Biomarker: Its Association With Alzheimer Pathology and Cognitive Impairment in Chinese Adults

    Journal of cachexia, sarcopenia and muscle

More on Mild cognitive impairment

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See all 35 papers on temporal muscle thickness