TCR Vd + Jd receptor diversity

1. IMMAX score is associated with TCR Vd + Jd receptor diversity in humans (b = -0.02 in both control and exposed samples).

   “Higher immune age was also negatively correlated with TCR Vd + Jd receptor diversity regardless of immune challenge”

   HumansBoth vehicle-control and recombinant SARS-CoV-2 spike protein-exposed samplesperipheral blood mononuclear cell

   Immune age is correlated with decreased TCR clonal diversity and antibody response to SARS-CoV-2

   Scientific reports·6 Jun 2025

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