Frontiers in Immunology
TIM3 and TIGIT-expressing CD4 T cells are impacted by kidney transplantation and associated with risk of infection
Cohort study of 91 peopleCD4
Papers on T central memory
123 papers4 new in 30 days
Friday, June 6
Thursday, May 22
Aging Cell
Physical Activity Modifies the Metabolic Profile of CD4⁺ and CD8⁺ T-Cell Subtypes at Rest and Upon Activation in Older Adults
Cross-sectional study of 10 peopleOxidative phosphorylation
EMBO Molecular Medicine
Restricting SLC7A5-mediated Leucine uptake in T cells prevents acute GVHD and maintains GVT response
Experiments in animalsBlood and immune system
Monday, May 5
bioRxiv
An Aged Microenvironment Increases CAR T Cell Cytotoxicity but Impairs Therapeutic Efficacy
Preprint: experiments in miceBlood and immune system
Wednesday, April 30
Frontiers in Medicine
Immunosenescence markers in T- and NK-cells according to the CD4/CD8 ratio in successfully treated people living with HIV
Cross-sectional study of 68 peopleCD4/CD8 ratio
Tuesday, April 22
Scientific Reports
Characterization of neutralizing versus binding antibody and T cell responses to varicella-zoster virus in the elderly
Cross-sectional study of 213 peopleImmune response
Monday, March 31
Laboratory Medicine
Peripheral lymphocyte phenotypic characteristics in healthy populations across the lifespan, from infancy to older adults
Cross-sectional study of 364 peopleMechanisms
Thursday, March 13
Immunity & Ageing
Compositional analysis of lymphocytes and their relationship with health outcomes: findings from the health and retirement study
Cross-sectional study of 6,250 peopleMechanisms
Wednesday, March 12
European Journal of Immunology
Age and Latent Cytomegalovirus Infection Do Not Affect the Magnitude of De Novo SARS-CoV-2-Specific CD8⁺ T Cell Responses
Cohort study in peopleImmune response
Monday, March 10
The Journal of Gene Medicine
Integrated Single-Cell Transcriptome and eQTL Analyses Reveal the Role of PZP in Aging and Chronic Kidney Disease
Cohort study in peopleKidney
Friday, March 7
Frontiers in Immunology
Short-term fasting before living kidney donation has an immune-modulatory effect
Randomized trial in 30 peopleBlood and immune system
Wednesday, March 5
Surgery for Obesity and Related Diseases
Bariatric surgery reverses morbid obesity-induced changes in the composition of circulating immune cells-a prospective cohort study
Cohort study in peopleBariatric surgery
Saturday, March 1
BMC Infectious Diseases
Lower immune senescence of T cell subsets among virologically suppressed Chinese men who have sex with men living with HIV in comparison with those ART naive
Cohort study in peopleImmune response
Tuesday, February 11
Frontiers in Immunology
Systematic review and quantitative meta-analysis of age-dependent human T-lymphocyte homeostasis
Meta-analysis of observational studiesCellular homeostasis
Wednesday, January 1
GSA 2024 Abstract
ASSOCIATION BETWEEN T CELL SUBSETS AND MORTALITY: FINDINGS FROM THE LONG LIFE FAMILY STUDY
Cohort study in peopleBlood and immune system
Wednesday, November 13
European Journal of Sport Science
Effects of concentric and eccentric exercise regimens on bioenergetic efficiency of lymphocytes in sedentary males
Randomized trial in 33 peopleInterventions
Friday, November 8
bioRxiv
Single-cell atlas of the human immune system reveals sex-specific dynamics of immunosenescence
Preprint: cross-sectional study of 982 peopleImmune response
Friday, October 25
Journal of Immunology
Development of a Spectral Flow Cytometry Analysis Pipeline for High-dimensional Immune Cell Characterization
Experiments in 11 miceBlood and immune system
Saturday, August 31
Wednesday, August 21
bioRxiv
Physical activity modifies the metabolic profile of CD4+ and CD8+ T cell subtypes at rest and upon activation in older adults
Preprint: cross-sectional study of 19 peopleOxidative phosphorylation
Tuesday, August 13
bioRxiv
The dynamics and longevity of circulating CD4⁺ memory T cells depend on cell age and not the chronological age of the host
Preprint: experiments in miceCD4
Tuesday, July 16
Renal Failure
Elucidating the causal nexus and immune mediation between frailty and chronic kidney disease: integrative multi-omics analysis
Mendelian randomization in 7,078 peopleImmune response
Monday, June 17
Thursday, June 13
Immunity & Ageing
Terminally differentiated effector memory T cells associate with cognitive and AD-related biomarkers in an aging-based community cohort
Cohort study of 84 peopleBiomarkers
Thursday, April 11
Frontiers in Cellular and Infection Microbiology
Pathological proliferation: a potential mechanism for poor CD4⁺ T cell recovery in people living with HIV
Cross-sectional study of 53 peopleCD4
Tuesday, April 2
Frontiers in Immunology
Immune cell phenotype and function patterns across the life course in individuals from rural Uganda
Cross-sectional study of 332 peopleImmune response
Thursday, March 28
Microbial Pathogenesis
Rapamycin improves the long-term T-cell memory and protective efficacy of tuberculosis subunit vaccine
Experiments in miceRapamycin
Thursday, March 7
Journal of Leukocyte Biology
In-depth human immune cellular profiling from newborn to frail
Cross-sectional study in peopleImmune response
Tuesday, February 27
Frontiers in Immunology
Homeodomain-only protein suppresses proliferation and contributes to differentiation- and age-related reduced CD8⁺ T cell expansion
Experiments in human cellsBlood and immune system