Spike-specific antibodies
3 papers study it1 more mentions it1 finding
- Humans3
Associations
1CD4+ senescent T cells
downin humans1
1 study
CD4+ senescent T cells
downin humans1
CD4+ senescent T cells are associated with spike-specific antibodies in humans.
“percentage of CD4+ Tsens was negatively correlated with spike-specific antibody titers, neutralization ability, and COVID-19 reactive IL-2+CD4+ T cells”
HumansCOVID-19peripheral bloodn = 100
Elevated CD4⁺ T Cell Senescence Associates with Impaired Immune Responsiveness in Severe COVID-19
Aging and diseaseFeb 14, 2024
Latest
Aging and Disease
Elevated CD4⁺ T Cell Senescence Associates with Impaired Immune Responsiveness in Severe COVID-19
Cohort study of 100 peopleCOVID-19
bioRxiv
CD4 + T cell senescence is associated with reduced reactogenicity in severe/critical COVID-19
Preprint: cohort study of 100 peopleCellular senescence
Nature Aging
Signs of immunosenescence correlate with poor outcome of mRNA COVID-19 vaccination in older adults
Cohort study in peopleMechanisms