SMC endorsement

1. Depressive symptoms predict SMC endorsement in humans (partial R 2 range: 0.281 to 0.304, all ps <0.001).

   “Depressive symptoms were a consistent and significant predictor of SMC endorsement across all models (partial R 2 range: 0.281 to 0.304, all p s <0.001).”

   Humansacross all models

   Risk Factors for Subjective Memory Concern Endorsement in Ethnoracially Diverse Middle and Late Life Adults

   AAIC 2025 abstract·23 Dec 2025

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1. Smoking predicts SMC endorsement in humans (b = -1.552, 95% CI: [-2.513, -0.592]).

   “Smoking status ( b = ‐1.552, p = 0.002, 95% CI: [‐2.513, ‐0.592]) explained a small, yet significant proportion of variance (partial R 2 =0.018, p <0.001) unique to adults >65.”

   Humansfully adjusted model

   Risk Factors for Subjective Memory Concern Endorsement in Ethnoracially Diverse Middle and Late Life Adults

   AAIC 2025 abstract·23 Dec 2025

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1. Diabetes predicts SMC endorsement in humans (b = 0.467, 95% CI: [0.279, 0.340]).

   “diabetes ( b = 0.467, p = 0.034, 95% CI: [0.279, 0.340], partial R 2 =0.004, p <0.001) explained a small, yet significant proportion of variance in SMC endorsement for adults ≤65.”

   Humansfully adjusted model

   Risk Factors for Subjective Memory Concern Endorsement in Ethnoracially Diverse Middle and Late Life Adults

   AAIC 2025 abstract·23 Dec 2025

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1. Traumatic brain injury predicts SMC endorsement in humans (b = 2.067, 95% CI: [0.235, 3.890]).

   “history of traumatic brain injury ( b = 2.067, p = 0.027, 95% CI: [0.235, 3.890], partial R 2 =0.005, p <0.001) and diabetes ( b = 0.467, p = 0.034, 95% CI: [0.279, 0.340], partial R 2 =0.004, p <0.001) explained a small, yet significant proportion of variance in SMC endorsement for adults ≤65.”

   Humansfully adjusted model

   Risk Factors for Subjective Memory Concern Endorsement in Ethnoracially Diverse Middle and Late Life Adults

   AAIC 2025 abstract·23 Dec 2025

More on Traumatic brain injury