Small HDL
Biomarker1 paper1 finding
- Humans1
Associations
1Dementia
downin humans1
1 study
Dementia
downin humans1
Small HDL lowers the risk of dementia in humans.
Humansplasma
HDL particle sizes show contrasting links to dementia risk · Alzheimer's & dementia : the journal of the Alzheimer's Association · 1 Oct 2026
Latest
2HDL particle sizes show contrasting links to dementia risk
In 23,790 older adults, higher small HDL levels tracked lower dementia risk (hazard ratios 0.89 to 0.91), while very large HDL tracked higher risk…In 23,790 older adults, higher small HDL levels tracked lower dementia risk (hazard ratios 0.89 to 0.91), while very large HDL tracked higher risk (1.10 to 1.14).
Small HDL particle count is linked to lower mortality
Top-quartile small HDL particle counts had all-cause mortality hazard ratios of 0.79 in men and 0.77 in women compared with bottom quartiles.Top-quartile small HDL particle counts had all-cause mortality hazard ratios of 0.79 in men and 0.77 in women compared with bottom quartiles.