There is 1 paper on single base substitution mutational signature 1 in aging research: 1 observational study in people.
1 paper studies it1 finding
See all 1 papers on single base substitution mutational signature 1
- Humans1
Interventions
1Body mass index
upin humans1
1 study
Body mass index
upin humans1
Body mass index is linked with higher single base substitution mutational signature 1 in humans (genetically predicted (polygenic score) BMI) (FDR = 0.03).
“(iii) increased single base substitution (SBS) mutational signature 1 (FDR = 0.03), implicating age-related mutagenesis”
Humansgenetically predicted (polygenic score) BMIendometrial tumorfemalesn = 354
The Tumor Multi-Omic Landscape of Endometrial Cancers Developed on a Background of Adiposity
Genes
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The Tumor Multi-Omic Landscape of Endometrial Cancers Developed on a Background of Adiposity
Genetic association study of 354 peopleMechanisms