SFRP2-expressing fibroblast abundance

1. Skin cancer is associated with SFRP2-expressing fibroblast abundance in humans.

   “SFRP2-expressing fibroblasts accumulated in aged skin and were also enriched in tumor-associated stroma”

   Humansskin cancerstumor-associated stroma

   Integrated single-cell and spatial transcriptomic analyses reveal an aging-associated fibroblast subtype linked to tumor progression in human skin

   Frontiers in medicine·8 Jul 2026

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