Serum BACE1 activity

There is 1 paper on serum BACE1 activity in aging research: 1 observational study in people.

Biomarker

1 paper studies it1 more mentions it4 findings

See all 2 papers on serum BACE1 activity

“Age was the strongest independent predictor of sBACE1 variance (β=0.425, p<0.0001)”
Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's DiseaseThe journal of prevention of Alzheimer's disease2022doi:10.14283/jpad.2022.78
  • Humans1

Interventions

3

Hypertension

upin humans1

1 study
  1. Hypertension is linked with higher serum BACE1 activity in humans (β=0.111).

    “hypertension (β=0.111, p<0.05)”

    Humans

    Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease

    The journal of prevention of Alzheimer's disease

More on Hypertension

Hdl cholesterol

downin humans1

1 study
  1. Hdl cholesterol is linked with lower serum BACE1 activity in humans (β=-0.168).

    “high density lipoprotein-cholesterol (HDL-C) (β=-0.168, p<0.0001)”

    Humans

    Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease

    The journal of prevention of Alzheimer's disease

More on Hdl cholesterol

Female sex

upin humans1

1 study
  1. Female sex is linked with higher serum BACE1 activity in humans (sex β=0.180, p<0.0001 in the overall model).

    “with women being more susceptible to higher sBACE1 activity than men”

    Humansfemales

    Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease

    The journal of prevention of Alzheimer's disease

More on Female sex

Associations

1

Age

upin humans1

1 study
  1. Age predicts serum BACE1 activity in humans (β=0.425).

    “Age was the strongest independent predictor of sBACE1 variance (β=0.425, p<0.0001)”

    Humans

    Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease

    The journal of prevention of Alzheimer's disease

More on Age

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