Serine racemase

2 papers study it8 more mention it2 findings

Animals2

Interventions

1

Amyloid-beta + 17beta-estradiol

upin mouse cells1

1 study

Amyloid-beta + 17beta-estradiol increases serine racemase in mouse cells.
“Neither Aβ nor 17β-estradiol increased SR, but the combination of both did in Müller cell cultures.”
Cellsin primary Müller cell cultures
Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse
Investigative ophthalmology & visual scienceJan 2, 2025

More on Amyloid-beta + 17beta-estradiol

Upstream

1

APP/PS1

upin mice1

1 study

APP/PS1 increases serine racemase in mice.
“SR levels were significantly higher in the retinas of 18- and 24-month-old male APP/PS1 mice”
AnimalsAlzheimer's disease modelretinamales
Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse
Investigative ophthalmology & visual scienceJan 2, 2025

More on APP/PS1

Latest

1 paper in 12 months

Investigative Ophthalmology & Visual ScienceJan 15

Age- and Sex-Specific Regulation of Serine Racemase in the Retina of an Alzheimer's Disease Mouse

Experiments in miceEye

Molecular NeurobiologyAug 10

Moderate-Intensity Exercise Induces Neurogenesis and Improves Cognition in Old Mice by Upregulating Hippocampal Hippocalcin, Otub1, and Spectrin-α

Experiments in miceInterventions

Cellular SignallingJul 28

Effect of moderate-intensity aerobic exercise on early oxidative stress and muscle atrophy in SAMP8 mice through modulation of the DAO/SRR and Nrf2/Keap1 pathways

Experiments in miceMuscle atrophy

AgingMay 18

Serine racemase expression profile in the prefrontal cortex and hippocampal subregions during aging in male and female rats

Experiments in ratsMechanisms

AgingApr 14

Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats

Experiments in ratsInterventions

International Journal of Molecular SciencesDec 24

Improved NMDA Receptor Activation by the Secreted Amyloid-Protein Precursor-α in Healthy Aging: A Role for D-Serine?

Experiments in animalsInterventions

Current Alzheimer ResearchAug 6

Serine Racemase Expression Differentiates Aging from Alzheimer's Brain

ReviewMechanisms

Frontiers in PsychiatryOct 29

An Overview of the Involvement of D-Serine in Cognitive Impairment in Normal Aging and Dementia

ReviewMechanisms

Frontiers in Molecular BiosciencesDec 18

Changes in Serine Racemase-Dependent Modulation of NMDA Receptor: Impact on Physiological and Pathological Brain Aging

ReviewMechanisms

Advances in GerontologyJan 1

COMPARATIVE MORPHOFUNCTIONAL CHARACTERISTICS OF ADULT AND OLD RAT VENTRAL HIPPOCAMPUS TO COMBINED STRESS INFLUENCE

Experiments in ratsMechanisms