Senescence-related serum biomarkers

1. Fisetin is associated with senescence-related serum biomarkers in humans.

   “The percent of C12FDG+ PBMCs and age-related serum biomarkers were decreased in a small subgroup of study participants taking the senolytic drug fisetin.”

   Humanssmall subgroup of participants taking fisetinserum

   Clinical validation of C₁₂FDG as a marker associated with senescence and osteoarthritic phenotypes

   Aging cell·6 May 2024

More on Fisetin

1. Senescence-related serum biomarkers are associated with C12FDG-positive PBMC percentage in humans.

   “There is an increase in the percent of circulating C12FDG+ PBMCs that is commensurate with increases in age and senescence-related serum biomarkers.”

   Humansperipheral blood mononuclear cells

   Clinical validation of C₁₂FDG as a marker associated with senescence and osteoarthritic phenotypes

   Aging cell·6 May 2024

More on C12FDG-positive PBMC percentage