SDNN index

There are 8 papers on SDNN index in aging research: 1 trial and 5 observational studies in people, 1 in animals, 1 review.

8 papers study it2 findings

See all 8 papers on SDNN index

“In addition, significant correlations were found between VO2 max and rMSSD (rho = 0.122, p = 0.032) and SDNN index (rho = 0.184, p = 0.001).”

The Relationship Between VO₂ Max and Heart Rate Variability Parameters in Individuals with High Risk for Cardiovascular DiseaseActa Cardiologica Sinica2026doi:10.6515/acs.202603_42(2).20250725a

Human trial1
Humans5
Animals1

Associations

2

Epicardial adipose tissue thickness

upin humans1

1 study

Epicardial adipose tissue thickness is associated with SDNN index in humans (ρ = 0.212).
“EAT thickness showed a positive association with the standard deviation of normal-to-normal intervals (SDNN) index of HRV (ρ = 0.212, p = 0.036).”
Humansn = 99
Correlation between epicardial adipose tissue and cognitive performance in older adults. A role for autonomic nervous system imbalance?
Frontiers in agingMar 26, 2026

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VO2 max

upin humans1

1 study

VO2 max is associated with SDNN index in humans (individuals at high risk of cardiovascular disease) (rho = 0.184, p = 0.001).
“In addition, significant correlations were found between VO2 max and rMSSD (rho = 0.122, p = 0.032) and SDNN index (rho = 0.184, p = 0.001).”
Humansindividuals at high risk of cardiovascular diseasen = 311
The Relationship Between VO₂ Max and Heart Rate Variability Parameters in Individuals with High Risk for Cardiovascular Disease
Acta Cardiologica SinicaMar 1, 2026

More on VO2 max

Latest

4 papers in 12 months

Frontiers in AgingApr 13

Correlation between epicardial adipose tissue and cognitive performance in older adults. A role for autonomic nervous system imbalance?

Cross-sectional study of 99 peoplePopulations

Acta Cardiologica SinicaMar 30

The Relationship Between VO₂ Max and Heart Rate Variability Parameters in Individuals with High Risk for Cardiovascular Disease

Cohort study of 311 peopleBiomarkers

Respiratory MedicineMar 14

Autonomic imbalance mediates sleep apnea-specific hypoxic burden and glucose metabolism in obstructive sleep apnea: A large-scale observational study

Cohort study of 2,470 peopleObstructive sleep apnea

MedicinaFeb 27

Heart Rate Variability Nomogram Predicts Atrial Fibrillation in Patients with Moderate to High Burden of Premature Ventricular Complexes

Cohort study of 187 peopleHeart rate variability

Journal of Equine Veterinary ScienceMay 16

Comparison of daily heart rate and heart rate variability in trained and sedentary aged horses

Study of 22 horsesInterventions

Food & FunctionJul 22

Association of polyunsaturated fatty acids with improved heart rate variability and cardiovascular events in patients with end-stage renal disease receiving maintenance dialysis: a systematic review and meta-analysis of randomized controlled trials

Meta-analysis of randomized trialsPolyunsaturated fatty acids

Archives of Gerontology and GeriatricsJan 23

Aging, heart rate variability and patterns of autonomic regulation of the heart

Cross-sectional study of 1,743 peopleMechanisms

Polskie Archiwum Medycyny WewnetrznejAug 19

Effect of short‑term testosterone replacement therapy on heart rate variability in men with hypoandrogen‑metabolic syndrome

Non-randomized trial in 80 peopleTestosterone