Salivary cytokines

1. Menopause was not clearly linked with salivary cytokines in humans after adjusting for multiple factors including age.

   “After adjusting for multiple factors, no significant difference was found in the salivary levels of the investigated cytokines between RMPW and PMW.”

   Humansafter adjusting for multiple factors including agesalivafemales

   Salivary inflammatory burden in pre- and postmenopausal women: Associations with body mass index, patient-reported health, serum cytokines, and periodontal parameters

   Journal of periodontology·Oct 18, 2023

More on Menopause

1. Olfactory–cognitive phenotype was not clearly linked with salivary cytokines in humans (CIH vs CNN).

   “Most salivary cytokines levels did not differ between groups.”

   HumansCIH vs CNN

   Salivary Dysbiosis Aligns with an Olfactory–Cognitive Phenotype in Aging

   medRxiv·Feb 16, 2026Preprint

1. Age is associated with salivary cytokines in humans.

   “increased levels of proinflammatory IL-1β and TNF-α and anti-IL-10, with a simultaneous decrease of IL-8”

   Humanssaliva

   IMMUNE PARAMETERS OF SALIVA IN PERSONS OF DIFFERENT AGE RESIDING IN ST. PETERSBURG AND LENINGRAD REGION

   Advances in gerontology = Uspekhi gerontologii·Jan 1, 2015