RYR1+ extracellular vesicles

1. Exercise increases RYR1+ extracellular vesicles in humans.

   “frequencies of RYR1+ EV subsets were significantly upregulated by chronic exercise”

   Human trialin two independent cohorts, including older adults with prediabetes or unknown prediabetes status

   RYR1⁺ skeletal muscle-derived extracellular vesicles are exercise responsive and associated with insulin action

   Journal of translational medicine·26 May 2026

More on Exercise

1. RYR1+ extracellular vesicles are associated with insulin action in humans.

   “greater RYR1+ EV frequencies associated with better insulin action”

   Humans

   RYR1⁺ skeletal muscle-derived extracellular vesicles are exercise responsive and associated with insulin action

   Journal of translational medicine·26 May 2026