RVWT/EDD ratio

1. RVWT/EDD ratio is associated with graft failure in humans.

   “Increased RVWT/EDD ratio is associated with worsening GLS, xenotransplant graft failure, and recipient mortality.”

   Human trialin cardiac xenotransplant recipientsheartn = 2

   Clinical Correlations with Serial Echocardiography and Global Longitudinal Strain in the First and Second Genetically Modified Porcine to Human Cardiac Xenotransplantation

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

More on Graft failure

1. RVWT/EDD ratio is associated with global longitudinal strain worsening in humans (r= 0.8).

   “For both xenografts, GLS worsened by an average of 42.3% (CI 42.2-42.4%) when the RVWT/EDD ratio reached 0.50 - 0.55, demonstrating a linear correlation (r= 0.8).”

   Human trialdemonstrating a linear correlationheartn = 2

   Clinical Correlations with Serial Echocardiography and Global Longitudinal Strain in the First and Second Genetically Modified Porcine to Human Cardiac Xenotransplantation

   AHA Scientific Sessions 2025 abstract·3 Nov 2025