End diastolic diameter

1. Cardiac xenotransplantation decreases end diastolic diameter in humans (-40.2% (CI 20.3-64.1%)).

   “From post-operative day (POD) 1 of xenotransplant to end-of-life, RVWT increased 80.9% (CI 95.6-118.5%) while EDD decreased 40.2% (CI 20.3-64.1%).”

   Human trialin cardiac xenotransplant recipientsheartn = 2

   Clinical Correlations with Serial Echocardiography and Global Longitudinal Strain in the First and Second Genetically Modified Porcine to Human Cardiac Xenotransplantation

   AHA Scientific Sessions 2025 abstract·3 Nov 2025

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