ROS-positive cells

1. Regulatory macrophage secretory products increase ROS-positive cells in human cells.

   “In HUVECep, SPMreg increased β-galactosidase activity and the proportion of ROS-positive cells, while reducing secretion of the SASP factor PAI-1 (P < 0.05 for all).”

   CellsEarly passage cells, passages 4–6human umbilical vein endothelial cells10 days

   Secretory products from regulatory macrophages modulate senescence in human endothelial cells: implications for cardiovascular aging and diseases

   BMC cardiovascular disorders·31 Mar 2026

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