Respiratory chain complex IV activity

1. COX17 increases respiratory chain complex IV activity in cells.

   “Furthermore, knockdown COX17 aggravated loss of complex IV activity, copper accumulation and RTECs senescence.”

   Cellsshown by COX17 knockdownrenal tubular epithelial cell

   MSCs-derived HGF alleviates senescence after AKI by modulating mitoSTAT3-controlled copper flux and respiration

   Stem cell research & therapy·29 Sep 2025

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