Rare variant polygenic risk score
1 paper1 finding
- Humans1
Associations
1Type 2 diabetes
upin silico1OR 3.1
1 study
Type 2 diabetes
upin silico1OR 3.1
Rare variant polygenic risk score predicts type 2 diabetes in silico (OR 3.1 vs. 0.82).
“Carriers of the HNF4A variant (p.Arg114Trp, OR = 7.9) had an average rvPRS corresponding OR of 3.1 compared to an average cvPRS corresponding OR of 0.82.”
In silicocarriers of p.Arg114Trp
ADA Scientific Sessions 2025 abstract13 Jun 2025
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