Nature Communications
Protein reduces brain immune cell activation in aged mice
Aged mice given eight injections of a youth-associated protein had a smaller share of inflammation-promoting brain immune cells than controls.Aged mice given eight injections of a youth-associated protein had a smaller share of inflammation-promoting brain immune cells than controls.
Mouse studyMechanisms
Who was studiedAged mice, against mice given a control solution
What changedIn aged mice, TIMP2 injections reduced microglial activation compared with mice given a control solution
The catchIsolated cells from treated aged mice took up less myelin