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Pro-inflammatory monocyte signatures

There is 1 paper on pro-inflammatory monocyte signatures in aging research: none in people yet, 1 in animals. The newest story, Nov 3, 2026: “Blood-cell gene loss impairs heart recovery in mice”.

Biomarker

1 paper studies it1 finding

1 new paper in 30 daysSee all 1 papers on pro-inflammatory monocyte signatures

“Patients with HF and KDM6A-driven CH show similar pro-inflammatory monocyte signatures.”
Hematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cellsNature cardiovascular research2026doi:10.1038/s44161-026-00887-3
  • Animals1

Associations

1

KDM6A-driven clonal hematopoiesis

upin humans1

1 study

  1. KDM6A-driven clonal hematopoiesis is associated with pro-inflammatory monocyte signatures in humans (heart failure).

    “Patients with HF and KDM6A-driven CH show similar pro-inflammatory monocyte signatures.”

    Humansheart failuremonocyte

    Blood-cell gene loss impairs heart recovery in mice

    Nature cardiovascular research

More on KDM6A-driven clonal hematopoiesis

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Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
Nature Cardiovascular Research

Blood-cell gene loss impairs heart recovery in mice

In mouse experiments, blocking an immune signal counteracted the harmful heart effects of losing KDM6A in blood-forming cells.In mouse experiments, blocking an immune signal counteracted the harmful heart effects of losing KDM6A in blood-forming cells.

Mouse studyMechanisms
Paper

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