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KDM6A-driven clonal hematopoiesis

Disease

1 finding

“Patients with HF and KDM6A-driven CH show similar pro-inflammatory monocyte signatures.”
Hematopoietic loss of KDM6A impairs cardiac recovery in heart failure via epigenetic reprogramming of myeloid cellsNature cardiovascular research2026doi:10.1038/s44161-026-00887-3

Associations

1

Pro-inflammatory monocyte signatures

upin humans1

1 study

  1. KDM6A-driven clonal hematopoiesis is associated with pro-inflammatory monocyte signatures in humans (heart failure).

    “Patients with HF and KDM6A-driven CH show similar pro-inflammatory monocyte signatures.”

    Humansheart failuremonocyte

    Blood-cell gene loss impairs heart recovery in mice

    Nature cardiovascular research

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