pre-ART inflammatory markers

1. Low CD4/CD8 ratio is associated with pre-ART inflammatory markers in humans.

   “R < 0.8 showed a differential inflammatory profile compared to R > 1.2 (increased β2-microglobulin, D-dimers and IP-10 before ART).”

   HumansVirally suppressed HIV infection, CD4≥500; CD4/CD8 ratio <0.8 versus >1.2Three years of ART

   The persistence of low CD4/CD8 ratio in chronic HIV-infection, despite ART suppression and normal CD4 levels, is associated with pre-therapy values of inflammation and thymic function

   Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·22 Aug 2024

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