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PME/PDE

Biomarker

1 paper studies it2 findings

Upstream

2

Parkinson's disease

downin humans1

1 study

  1. Parkinson's disease decreases PME/PDE in humans (MD = -0.050, p = 0.023).

    “PD patients showed decreases in PME/PDE in the putamen (MD = -0.050, p = 0.023)”

    Reviewcompared to controlsputamen

    Neuroenergetic alterations in neurodegenerative diseases: A systematic review and meta-analysis of in vivo³¹P-MRS studies

    Ageing research reviews

More on Parkinson's disease

Alzheimer's disease

upin humans1

1 study

  1. Alzheimer's disease increases PME/PDE in humans (MD = 0.049, p = 0.0003).

    “Compared to controls, AD patients had a higher ratio of phosphomonoesters/phosphodiesters (PME/PDE) in the frontal lobe (MD = 0.049, p = 0.0003)”

    Reviewcompared to controlsfrontal lobe

    Neuroenergetic alterations in neurodegenerative diseases: A systematic review and meta-analysis of in vivo³¹P-MRS studies

    Ageing research reviews

More on Alzheimer's disease

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