PHGDH

1 paper studies it13 more mention it

Humans1

Latest

4 papers in 12 months

Journal of Alzheimer's DiseaseSep 16

L-serine-enriched diet restores impaired adult neurogenesis in the hippocampus of 3xTg-AD mice

Experiments in miceInterventions

MetabolitesMar 27

Exercise Reprograms the Spatial Function of Phosphoglycerate Dehydrogenase of a Pathogenic Nuclear Transcription Factor (PHGDH): A Narrative Review

Current Issues in Molecular BiologyJan 30

The Senescence-SASP Landscape in Colon Adenocarcinoma: Prognostic and Therapeutic Implications

Computational studyBiomarkers

PLOS OneJan 9

Mechanisms of cellular senescence combined with molecular docking strategies: A biomarker study of potential therapeutic targets for allergic rhinitis

Computational studyCellular senescence

bioRxivJun 4

Serine auxotrophy is a targetable vulnerability driven by PSAT1 suppression in AML

Preprint: experiments in miceInterventions

AgingApr 9

Pharmacological recapitulation of the lean phenotype induced by the lifespan-extending sulfur amino acid-restricted diet

Experiments in miceInterventions

The Journals of Gerontology, Series AMar 16

Human Peripheral Blood Leukocyte Transcriptome-Based Aging Clock Reveals Acceleration of Aging by Bacterial or Viral Infections

Cohort study of 1,558 peopleInfectious disease

Frontiers in ImmunologyMay 13

Screening and validation of atherosclerosis PAN-apoptotic immune-related genes based on single-cell sequencing

Case-control study in peopleCarotid atherosclerosis

Current Issues in Molecular BiologyApr 26

Serine Metabolism Regulates the Replicative Senescence of Human Dental Pulp Cells through Histone Methylation

Experiments in human cellsMethionine and one-carbon metabolism

Cell ResearchSep 20

Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate

Experiments in miceAmino acid metabolism