PHASE Index

PHASE Index improves discrimination of HF-related events in humans (c-index 0.723 vs. 0.587).

“demonstrated superior discrimination compared with BNP alone (c-index 0.723 vs. 0.587, P < 0.05).”

HumansStage B heart failure with BNP levels of 35-100 pg/mL; compared with BNP alone10 years

Risk stratification of Stage B heart failure with BNP levels of 35-100 pg/mL: development of the PHASE Index from the CHART-2 Study

European heart journal open·5 Oct 2026