PEV reporter aging clock

PEV reporter aging clock is associated with lifespan in flies.

“Within a single population, animals with enhanced PEV phenotypes live longer than those with more suppressed PEV phenotypes”

Model organisms

Position effect variegation (PEV) as an aging clock: visualization of age-dependent loss of heterochromatin and longevity associated with enhanced heterochromatin

Scientific reports·8 Jan 2026