Papers on osteoclast formation

158 papers8 new in 30 days

Wednesday, May 13

Ecotoxicology and Environmental SafetyMay 13

6:2 Cl-PFESA exacerbates osteoporosis by activating the Nos2-ROS-mtDNA-STING pathway in osteoclasts: An emerging osteoporotic threat

Experiments in miceOxidative stress and ROS signaling

Paper

Saturday, May 9

The Journal of Biological ChemistryMay 9

Geranylgeraniol promotes osteoblast differentiation and inhibits osteoclastogenesis through MAPK and nuclear receptor signaling

Experiments in mouse cellsInterventions

Paper

Thursday, April 9

Bioactive MaterialsApr 9

Epigenetic reprogramming periosteum promotes aging critical segmental bone defect repair via methylation remodeling

Experiments in miceBones and joints

Paper

Thursday, April 2

Current Medical ScienceApr 2

LATS1/2 Inhibitor Attenuates Osteoclast Differentiation via Hippo-YAP/TAZ Signaling Pathway and Alleviates Osteoporosis in Ovariectomized Rats

Experiments in ratsHippo–YAP signaling

Paper

Monday, March 30

European Journal of PharmacologyMar 30

Coixol attenuates osteoclastogenesis and ovariectomy-induced bone loss via the HIF-1α-mediated suppression of NF-κB signaling

Experiments in miceBone loss

Paper

Sunday, March 29

BoneMar 29

Systemic administration of osteoblast-derived collagenase released extracellular vesicles restores trabecular bone loss in ovariectomized mice

Experiments in miceBones and joints

Paper

Saturday, March 28

AntioxidantsMar 28

Synthetic Novel Flavonoids SZQ-4 Suppress Osteoclastogenesis and Ameliorate Osteoporosis via Inhibiting Reactive Oxygen Species and Regulating SIRT3

Experiments in micePostmenopausal osteoporosis

Paper

LifeMar 28

Prevalence of Low Bone Density and Fracture Risk Assessed with the FRAX Tool in German Patients with Axial Spondyloarthritis: A Cross-Sectional Study

Cross-sectional study of 58 peopleFRAX

Paper

Monday, March 23

PhytomedicineMar 23

A novel METTL3 inhibitor nimbolide ameliorates osteoporosis via orchestrating osteoclastogenesis in an m6A-dependent manner

Experiments in miceOsteoporosis

Paper

Monday, March 16

Current Pharmaceutical DesignMar 16

Physcion Alleviates Osteoporotic Bone Loss by Inhibiting Osteoclast Formation and Promoting Osteoblast Differentiation

Experiments in miceOsteoporosis

Paper

Frontiers in EndocrinologyMar 16

Modeling rebound bone loss following denosumab discontinuation and sequential zoledronate therapy in TgRANKL osteoporotic mice

Experiments in miceDenosumab

Paper

Friday, March 6

Biochemical PharmacologyMar 6

Integration of multi-omics and machine learning to reveal the anti-osteoporosis effects of Hederagenin by inhibiting lipid peroxidation via the GPX4/p-STAT1/PTGS2 axis

Experiments in miceOsteoporosis

Paper

Monday, March 2

Biochemical and Biophysical Research CommunicationsMar 2

Genistein alleviates Osteoporosis by inhibiting the differentiation and autophagy of osteoclasts via regulating the CYLD/p62/RANKL axis

Experiments in ratsOsteoporosis

Paper

Friday, February 27

Journal of Medicinal ChemistryFeb 27

A Novel Nrf2 Activator Suppresses Osteoclastogenesis and Ovariectomy-Induced Bone Loss by Directly Interfering Keap1-Nrf2 Protein-Protein Interaction

Experiments in miceBones and joints

Paper

PharmaceuticalsFeb 27

Design, Synthesis and Biological Evaluation of Novel Furanocoumarin Derivatives: Validation of Anti-Osteoporotic Efficacy In Vitro and In Vivo

Experiments in miceOsteoporosis

Paper

Sunday, February 15

PhytomedicineFeb 15

Targeting muscle-bone crosstalk with hormone-like peptides: Systems approach reveals RGHGP-mediated suppression of LAMB1-MAPK osteoclastogenesis

Experiments in animalsBones and joints

Paper

Friday, February 13

Bone ResearchFeb 13

Estradiol regulates osteoclast sialylation via ST3Gal1 in postmenopausal osteoporosis

Experiments in animalsBones and joints

Paper

Thursday, February 12

Advanced ScienceFeb 12

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

Experiments in miceBones and joints

Paper

Wednesday, February 11

Immunity & AgeingFeb 11

Aging-induced decrease in progenitor B cells enhances the osteoclastogenesis of bone marrow macrophages via ROS-activated Fos/CCL3 signaling‌ pathway

Experiments in miceOxidative stress and ROS signaling

Paper

Saturday, February 7

Phytotherapy ResearchFeb 7

Desmethoxyyangonin, a Potent Cannabinoid Receptor 2 Agonist, Alleviates Bone Loss in Ovariectomized Mice via Dual Regulation of Osteoblast and Osteoclast Function

Experiments in miceBone loss

Paper

Friday, February 6

The Journal of Infectious DiseasesFeb 6

Frailty in People with HIV Is Linked to Inflammation, Bone Health, and T-Cell Exhaustion

Cross-sectional study in peopleInflammation

Paper

Wednesday, February 4

Cell Biology and ToxicologyFeb 4

LncRNA-Gm5532 deficiency alleviates bone resorption by inhibiting mitochondrial respiration through iASPP/NRF2

Experiments in miceNRF2–KEAP1 antioxidant response

Paper

Friday, January 30

EJHaemJan 30

Rosuvastatin in Combination With Bortezomib Promotes Osteogenesis in Myeloma Bone Disease by Inhibiting the Secretion of CCL3

Experiments in miceStatins

Paper

Wednesday, January 28

Frontiers in PharmacologyJan 28

γ-Mangostin attenuates osteoclastogenesis and bone resorption by suppressing the PI3K/AKT/NF-κB pathway

Experiments in ratsBones and joints

Paper

Tuesday, January 27

International Journal of Oral ScienceJan 27

Periodontitis-associated salivary microbiota exacerbates systemic osteoclastogenesis via gut modulation and tryptophan metabolism suppression in ovariectomized mice

Experiments in micePeriodontitis

Paper

Friday, January 23

Experimental & Molecular MedicineJan 23

Rgnef regulates bone mass through the activation of RhoA and Rac1

Experiments in miceBones and joints

Paper

Monday, January 12

International Journal of Biological SciencesJan 12

Gut Metabolite Indoleacrylic Acid Suppresses Osteoclast Formation by AHR mediated NF-κB Signaling Pathway

Experiments in miceGut and microbiome

Paper

Friday, January 2

Free Radical Biology & MedicineJan 2

The novel Nrf2 agonist neobavaisoflavone attenuates periodontitis by inhibiting osteoclastogenesis through iron homeostasis regulation and senescence suppression

Experiments in micePeriodontitis

Paper

Wednesday, December 17

Bioactive MaterialsDec 17

Designed bone-targeting ROS-responsive nanoplatform for precision glycolysis inhibition in postmenopausal osteoporosis

Experiments in animalsInterventions

Paper

Saturday, December 13

Experimental GerontologyDec 13

Hepcidin inhibits osteoclast differentiation to alleviate osteoporosis by modulating the p53/miR-34a/Trem2 axis

Experiments in miceTREM2

Paper