Genome Medicine·Sep 18Machine learning identifies microbiome and clinical predictors of sustained weight loss following prolonged fastingRandomized trial in 38 peopleGut and microbiomePaper
Bone·Aug 13The association of gut microbiome composition with musculoskeletal features in middle-aged and older adults: A two-cohort joint studyCohort study in peopleBones and jointsPaper
Microorganisms·Mar 28Gut Microbiota Affects Age-Related Plasma MetabolitesCohort study in peopleAmino acid metabolismPaper
Nature Communications·Feb 4Gut microbiota-dependent 24-hydroxycholesterol metabolism contributes to capsaicin-induced amelioration of Alzheimer's disease-like pathology in miceExperiments in miceAlzheimer's diseasePaper
bioRxiv·Jan 27Effects of Liraglutide on Gut Bacterial Community DynamicsPreprint: experiments in 24 miceLiraglutidePaper
Experimental Gerontology·Nov 7Gut microbiota composition and long-term physical activity in healthy older adults at high and low performance levelsCross-sectional study in peopleGut and microbiomePaper
Gut Microbes·Oct 30Gut enterotype- and body mass index (BMI)-dependent effects of anthocyanin supplementation on gut microbiota composition in individuals at risk for cognitive decline: a randomized placebo-controlled trialRandomized trial in 99 peopleAnthocyaninsPaper
Food and Chemical Toxicology·Oct 11Thallium exposure disturbs gut microbiota composition, metabolic function, and host gut energy metabolism in aged miceExperiments in miceMicrobiome compositionPaper
Frontiers in Nutrition·Aug 22High-calcium milk improves osteoporosis in postmenopausal women by regulating intestinal flora and steroid hormone biosynthesisRandomized trial in 97 peopleOsteoporosisPaper
Food & Function·Aug 5A standardised saffron extract improves subjective and objective sleep quality in healthy older adults with sleep complaints: results from the gut-sleep-brain axis randomised, double-blind, placebo-controlled pilot studyRandomized trial in 52 peopleInterventionsPaper
Toxicology and Applied Pharmacology·Aug 1Miconazole alleviates colitis by suppressing colonic senescence, NF-κB Signaling and gut microbiota modulationExperiments in animalsColitisPaper
medRxiv·Mar 4The association of gut microbiome composition with musculoskeletal features in middle-aged and older adults: a two-cohort joint studyPreprint: cohort study of 1,249 peopleGut and microbiomePaper
Nutrients·Aug 31The Effects of Caloric Restriction and Clinical Psychological Intervention on the Interplay of Gut Microbial Composition and Stress in WomenRandomized trial in 41 peopleDietary restrictionPaper
Frontiers in Microbiology·Oct 4Multi-omics analysis reveals substantial linkages between the oral-gut microbiomes and inflamm-aging molecules in elderly pigsStudy of 45 pigsMicrobiome compositionPaper
Microbiological Research·Jul 21Characterization of gut microbiota in mouse models of aging and sarcopeniaExperiments in miceMicrobiome compositionPaper
Nutrients·Oct 28Effects of Lactiplantibacillus plantarum OLL2712 on Memory Function in Older Adults with Declining Memory: A Randomized Placebo-Controlled TrialRandomized trial in 78 peopleInterventionsPaper
Journal of Endocrinological Investigation·Oct 12Calorie restriction ameliorates hyperglycemia, modulates the disordered gut microbiota, and mitigates metabolic endotoxemia and inflammation in type 2 diabetic ratsExperiments in ratsDietary restrictionPaper
Food & Nutrition Research·Nov 16Dietary lactoferrin has differential effects on gut microbiota in young versus middle-aged APPswe/PS1dE9 transgenic mice but no effects on cognitive functionExperiments in animalsInterventionsPaper
Frontiers in Cell and Developmental Biology·Oct 30P16 I NK 4a Deletion Ameliorates Damage of Intestinal Epithelial Barrier and Microbial Dysbiosis in a Stress-Induced Premature Senescence Model of Bmi-1 DeficiencyExperiments in miceMicrobiome compositionPaper
Frontiers in Nutrition·Jul 29NMN Maintains Intestinal Homeostasis by Regulating the Gut MicrobiotaExperiments in miceNicotinamide mononucleotidePaper
Pharmaceuticals·Jun 23Nrf2/ARE Activators Improve Memory in Aged Mice via Maintaining of Mitochondrial Quality Control of Brain and the Modulation of Gut MicrobiomeExperiments in miceGut and microbiomePaper
International Journal of Molecular Sciences·Jun 3A Tryptophan-Deficient Diet Induces Gut Microbiota Dysbiosis and Increases Systemic Inflammation in Aged MiceExperiments in miceMicrobiome compositionPaper
Neurochemistry International·Mar 9Voluntary wheel running is capable of improving cognitive function only in the young but not the middle-aged male APPSwe/PS1De9 miceExperiments in animalsInterventionsPaper
Frontiers in Microbiology·Mar 9Ramadan Fasting Leads to Shifts in Human Gut Microbiota Structured by Dietary CompositionCohort study in peopleRamadan fastingPaper
Aging·May 27Dietary type 2 resistant starch improves systemic inflammation and intestinal permeability by modulating microbiota and metabolites in aged mice on high-fat dietExperiments in miceGut and microbiomePaper
Animal Microbiome·Sep 5Impaired glucose metabolism and altered gut microbiome despite calorie restriction of ob/ob miceExperiments in miceDietary restrictionPaper
Microbiome·Mar 15Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversityTrial in peopleInterventionsPaper
Immunity & Ageing·Dec 7Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiotaExperiments in animalsMechanismsPaper