Oral microbiome composition

Biomarker

1 paper2 findings

Associations

2

Edentulism or fewer teeth

mixedin humans1

1 study
  1. Edentulism or fewer teeth is associated with oral microbiome composition in humans.

    “These patterns were reversed in frail individuals and older adults with edentulism or fewer teeth compared with healthy older adults.”

    Reviewcompared with healthy older adultsoral cavity

    From culture-based to 16S sequencing approaches: oral microbiota changes in aging, frailty, and oral hypofunction - a systematic review

    BMC oral health28 Apr 2026

Frailty

mixedin humans1

1 study
  1. Frailty is associated with oral microbiome composition in humans.

    “significant compositional changes were observed in frailty.”

    Reviewfrail individualsoral cavity

    From culture-based to 16S sequencing approaches: oral microbiota changes in aging, frailty, and oral hypofunction - a systematic review

    BMC oral health28 Apr 2026

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PLOS One

Oral bacteria linked to cognition in UK and Belgian adults

Across 60 healthy younger and older adults in the UK and Belgium, researchers found shared bacterial associations with cognitive performance despite geographic microbiome…Across 60 healthy younger and older adults in the UK and Belgium, researchers found shared bacterial associations with cognitive performance despite geographic microbiome differences.

Cohort study of 60 peoplePopulations