Orai1

1 paper studies it14 more mention it

Humans1

Latest

1 paper in 12 months

Journal of Ginseng ResearchSep 10

Direct targeting of ORAI1 by ginsenoside Rg3 modulates calcium signaling and senescence-associated AMPK-NRF2 activation

Experiments in human cellsInterventions

International Journal of Molecular SciencesSep 27

Estrogens and Antioxidants Prevent the Formation of Tubular Aggregates in Aging Male Mice

Experiments in miceEstrogen

BiomedicinesAug 31

Constitutive, Muscle-Specific Orai1 Knockout Results in the Incomplete Assembly of Ca²⁺ Entry Units and a Reduction in the Age-Dependent Formation of Tubular Aggregates

Experiments in miceMuscle

International Journal of Molecular SciencesSep 9

Upregulation of Orai Channels Contributes to Aging-Related Vascular Alterations in Rat Coronary Arteries

Experiments in animalsMechanisms

CellsNov 27

Functional Role of STIM-1 and Orai1 in Human Microvascular Aging

Study of 45 peopleMechanisms

Journal of Bone and Mineral MetabolismAug 11

Defective bone repletion in aged Balb/cBy mice was caused by impaired osteoblastic differentiation

Experiments in miceStem cell differentiation

Human ImmunologyJun 7

Sex-dependent effect of aging on calcium signaling and expression of TRPM2 and CRAC channels in human neutrophils

Cross-sectional study in peopleMechanisms

Human ImmunologyDec 12

Aging does not affect calcium response to CCL2 and LPS in human monocytes

Study in peopleMechanisms

Mechanisms of Ageing and DevelopmentOct 27

Ageing-induced hypercontractility is related to functional enhancement of STIM/Orai and upregulation of Orai 3 in rat and human penile tissue

Study in peopleMechanisms

PLOS OneJul 30

Aging increases senescence, calcium signaling, and extracellular matrix deposition in human airway smooth muscle

Experiments in cellsMechanisms