Nucleotide content at fourfold degenerate synonymous positions

1. mtDNA A H >G H mutational bias are associated with nucleotide content at fourfold degenerate synonymous positions in silico.

   “this mutational bias from A H to G H affects nucleotide content at the fourfold degenerative synonymous positions leading to a deficit of A H”

   In silicoespecially pronounced in long-lived mammals

   Mammalian mitochondrial mutational spectrum as a hallmark of cellular and organismal aging

   bioRxiv (Cold Spring Harbor Laboratory)·Mar 26, 2019Preprint

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