Nuclear blebbing
2 papers1 finding
- Cells2
Interventions
1Everolimus
downin human cells1
1 study
Everolimus
downin human cells1
Everolimus decreases nuclear blebbing in human cells.
“there is a significant improvement in nuclear blebbing”
Cellsin several laminopathy fibroblast cell lines
Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts
Proceedings of the National Academy of Sciences of the United States of America26 Mar 2018
Latest
PNAS
Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts
Experiments in human cellsmTOR inhibitors
Science Translational Medicine
Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
Experiments in human cellsRapamycin