Neutrophil fraction

1. GrimAge is associated with neutrophil fraction in humans (R2 = 0.74).

   “Notably, GrimAge changes strongly correlated with fluctuations in leukocyte composition, particularly neutrophil fraction (R2 = 0.74, P < 0.001).”

   Human trial6-monthn = 42

   Epigenetic age deceleration reflects exercise-induced cardiorespiratory fitness improvements

   GeroScience·17 Jan 2026

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